In 1967, France Roque began her journalist career in Greece working as a correspondent for the French leading radio RTL. In 1972, she joined the national French Television Antenne 2 as a reporter for three years. She thereafter became chief editor for the weekly newsmagazine VSD for two years before joining the daily newspaper Le Matin de Paris as editor in chief in charge of the weekend edition. In 1978, she was appointed as chief editor of the well-known Figaro Magazine. From 1986 to 1992, she was editor in chief of Sipa Press International and interviewed most of the world's top leaders. From 1992 to 2018 she was in charge of public relations for the Nouvel Observateur group (which includes Le Nouvel Observateur, leader of the newsmagazine in France but also the monthly economic magazine Challenges and the monthly scientific review Science & Avenir). In 2000, France Roque co-created the publishing house Editions Saint-Simon that she runs today. In 2007, she created the European Book Prize with Jacques Delors. Every year, they reward a writer that conveys a positive image of Europe during a ceremony at the European Parliament in Brussels.